HMG20A and DCTN4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		HMG20A	DCTN4
Description		high mobility group 20A	dynactin subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 30718926 28869590)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 28604730)
Interacting Genes		25 interacting genes: ADD1 BRAP CCDC136 CCNK CFAP53 DCTN4 DTNA DTNB FBXO7 FMNL1 GTF2A1L HMG20B HPCAL1 KPNA2 MAGOHB PHF21A PSTPIP1 PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC	7 interacting genes: ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1
Entrez ID		10363	51164
HPRD ID		16116	13126
Ensembl ID		ENSG00000140382	ENSG00000132912
Uniprot IDs		B4DMG1 Q9NP66	A0A0S2Z5D4 Q9NSJ5 Q9UJW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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