SF3A1 and SF1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3A1	SF1
Description		splicing factor 3a subunit 1	splicing factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body
	Molecular Function	RNA Binding Protein Binding	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS		Delirium ( 29631748) Urinary albumin-to-creatinine ratio ( 31511532)	Urate levels ( 21768215)
Interacting Genes		17 interacting genes: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 WBP4 WDR77	43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		10291	7536
HPRD ID		06903	03306
Ensembl ID		ENSG00000099995	ENSG00000168066
Uniprot IDs		A0A024R1K8 Q15459	A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637
PDB IDs		1ZKH 2DT6 2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9	1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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