SF1 and ILF3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		SF1	ILF3
Description		splicing factor 1	interleukin enhancer binding factor 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		mRNA Splicing - Major Pathway
Drugs		Artenimol
Diseases
GWAS		Urate levels ( 21768215)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Ischemic stroke ( 29531354) Obesity-related traits ( 23251661) Psoriasis ( 25903422 25574825 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Stroke ( 29531354) Systemic lupus erythematosus ( 28714469)
Interacting Genes		43 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	30 interacting genes: DHX9 EIF2AK2 EP300 ERG ESR1 FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 PRMT5 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 UBC XAB2 XPO5 ZNF346 ZNF830
Entrez ID		7536	3609
HPRD ID		03306	04420
Ensembl ID		ENSG00000168066	ENSG00000129351
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	A0A024R7C7 Q12906
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX	2L33 3P1X
Enriched GO Terms of Interacting Partners?
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