SF3A1 and SF3A2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (biochemical, two hybrid, two hybrid, affinity chromatography technology)
HPRD (in vitro)

		SF3A1	SF3A2
Description		splicing factor 3a subunit 1	splicing factor 3a subunit 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of Neuron Projection Development U2-type Prespliceosome Assembly
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs			Copper
Diseases
GWAS		Delirium ( 29631748) Urinary albumin-to-creatinine ratio ( 31511532)	Myocardial infarction ( 24916648) Pulse pressure ( 26390057)
Interacting Genes		17 interacting genes: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 WBP4 WDR77	8 interacting genes: APBB1 HTATSF1 PRPF40A RETN SF3A1 SMURF2 TCERG1 WBP4
Entrez ID		10291	8175
HPRD ID		06903	02877
Ensembl ID		ENSG00000099995	ENSG00000104897
Uniprot IDs		A0A024R1K8 Q15459	Q05DF2 Q15428
PDB IDs		1ZKH 2DT6 2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9	5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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