SF3A1 and WDR77

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SF3A1	WDR77
Description		splicing factor 3a subunit 1	WD repeat domain 77
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding Methyl-CpG Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS		Delirium ( 29631748) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		17 interacting genes: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 WBP4 WDR77	44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PITRM1 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		10291	79084
HPRD ID		06903	14387
Ensembl ID		ENSG00000099995	ENSG00000116455
Uniprot IDs		A0A024R1K8 Q15459	A0A024R0H7 Q9BQA1
PDB IDs		1ZKH 2DT6 2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9	4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S
Enriched GO Terms of Interacting Partners?
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