TRAP1 and TPM3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TRAP1	TPM3
Description		TNF receptor associated protein 1	tropomyosin 3
Image
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Membrane	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	RNA Binding Tumor Necrosis Factor Receptor Binding Protein Binding ATP Binding Protein Kinase Binding Unfolded Protein Binding	Molecular_function Protein Binding Actin Filament Binding
	Biological Process	Protein Folding Translational Attenuation Chaperone-mediated Protein Folding Negative Regulation Of Cellular Respiration Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide	Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways		Respiratory electron transport	Striated Muscle Contraction Smooth Muscle Contraction
Drugs			Phenethyl Isothiocyanate
Diseases			Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Estimated glomerular filtration rate ( 31152163 31451708) Granulocyte count ( 27863252) Infliximab-induced mucosal healing in Crohn's disease ( 31039275) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Neutrophil count ( 27863252) Non-alcoholic fatty liver disease activity score ( 31311600) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252)	Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		15 interacting genes: APP ESX1 EXT1 EXT2 HGS MCPH1 PSMC4 RB1 SMAD4 TGFBR1 TGFBR2 TLR1 TLR6 TNFRSF1A TPM3	44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		10131	7170
HPRD ID		05868	01840
Ensembl ID		ENSG00000126602	ENSG00000143549
Uniprot IDs		A0A140VJY2 Q12931 Q53FS6	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs		4Z1F 4Z1G 4Z1H 4Z1I 5F3K 5F5R 5HPH 5Y3N 5Y3O	6OTN
Enriched GO Terms of Interacting Partners?
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