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LNX1 and SSTR3
Number of citations of the paper that reports this interaction (PMID
22889411
)
1
Data Source:
BioGRID
(two hybrid)
LNX1
SSTR3
Gene Name
ligand of numb-protein X 1, E3 ubiquitin protein ligase
somatostatin receptor 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Nonmotile Primary Cilium
Neuron Projection
Ciliary Membrane
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
Somatostatin Receptor Activity
Protein Binding
Neuropeptide Binding
Biological Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
Organelle Organization
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Neuropeptide Signaling Pathway
Cell-cell Signaling
Synaptic Transmission
Spermatogenesis
Negative Regulation Of Cell Proliferation
Hormone-mediated Apoptotic Signaling Pathway
Cerebellum Development
Forebrain Development
Somatostatin Signaling Pathway
Response To Starvation
Regulation Of Insulin Secretion
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Estradiol Stimulus
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Class A/1 (Rhodopsin-like receptors)
Assembly of the primary cilium
Metabolic disorders of biological oxidation enzymes
BBSome-mediated cargo-targeting to cilium
GPCR ligand binding
GPCR downstream signaling
Peptide ligand-binding receptors
G alpha (i) signalling events
Drugs
Diseases
GWAS
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
5 interactors:
CORT
GNAI1
LNX1
SST
TP53
Entrez ID
84708
6753
HPRD ID
17287
01675
Ensembl ID
ENSG00000072201
ENSG00000183473
Uniprot IDs
Q8TBB1
P32745
Q86YF2
PDB IDs
3B76
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Response To Osmotic Stress
Synaptic Transmission
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Negative Regulation Of Macromitophagy
Oligodendrocyte Apoptotic Process
Cell-cell Signaling
Negative Regulation Of Helicase Activity
G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cell Aging
Positive Regulation Of Thymocyte Apoptotic Process
Hormone-mediated Apoptotic Signaling Pathway
Mitochondrial DNA Repair
Cell Surface Receptor Signaling Pathway
Regulation Of Mitochondrion Degradation
T Cell Proliferation Involved In Immune Response
B Cell Lineage Commitment
Glial Cell Apoptotic Process
Oxidative Stress-induced Premature Senescence
Apoptotic Signaling Pathway
ER Overload Response
Negative Regulation Of Macroautophagy
Stress-induced Premature Senescence
Positive Regulation Of T Cell Apoptotic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
DNA Strand Renaturation
DNA Damage Response, Signal Transduction Resulting In Transcription
Mitotic Cell Cycle Arrest
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Blood Coagulation
Hemostasis
Protein Oligomerization
Response To Nutrient Levels
Regulation Of Thymocyte Apoptotic Process
Replicative Senescence
Positive Regulation Of Mitochondrial Membrane Permeability
Determination Of Adult Lifespan
Positive Regulation Of Lymphocyte Apoptotic Process
Circadian Behavior
Response To Extracellular Stimulus
Mitochondrial DNA Metabolic Process
Positive Regulation Of Histone Deacetylation
Rhythmic Behavior
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Fibroblast Apoptotic Process
Positive Regulation Of Protein Oligomerization
Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
RRNA Transcription
Response To Drug
Tagcloud
?
3beta
analog
catenin
colon
colonic
downregulated
elucidated
gsk
immunocytochemistry
inactivated
ladder
methodology
modulation
myc
numerous
octreotide
preliminary
promoted
somatostatin
sstr1
sstr2
sstr4
sstr5
sstrs
stimulating
sw480
tcf
wnt
Tagcloud (Difference)
?
3beta
analog
catenin
colon
colonic
downregulated
elucidated
gsk
immunocytochemistry
inactivated
ladder
methodology
modulation
myc
numerous
octreotide
preliminary
promoted
somatostatin
sstr1
sstr2
sstr4
sstr5
sstrs
stimulating
sw480
tcf
wnt
Tagcloud (Intersection)
?