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LNX1 and FHL3
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LNX1
FHL3
Gene Name
ligand of numb-protein X 1, E3 ubiquitin protein ligase
four and a half LIM domains 3
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Stress Fiber
Nucleus
Focal Adhesion
Z Disc
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
Actin Binding
Zinc Ion Binding
Biological Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
Muscle Organ Development
Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
88 interactors:
A1CF
ACTB
ADAM15
ADAMTSL4
AIMP2
AMBP
C14orf105
C9orf116
CDC25B
CDC42EP1
CNNM3
CORO1A
CSF1
CTBP2
DCDC2B
E2F8
EFCAB12
EPHA10
EPM2AIP1
FAM154A
FAM71C
FAM90A1
FBXL18
FHL2
FHL5
FOSL2
GATA2
GCM2
HIPK1
HYAL2
ITGA7
KIRREL2
KLF3
KLF8
KRTAP12-1
KRTAP12-2
KTI12
LASP1
LMO2
LNX1
MAPK1
MED15
MPZL1
MRPL27
MYBPC1
MYBPHL
MZF1
NPRL3
P4HA2
PAK7
PATL1
PHC2
PHF21A
PLEKHF2
PPIG
PTPN6
QRICH1
RAD21
RBM42
RFX3
RFX6
RHEBL1
RNMTL1
SAP30BP
SLAIN1
SLC25A46
SLC44A3
SMAD2
SMAD3
SMAD4
SNRPG
SREBF2
SRF
TMX3
TRAF3IP2
TRIM27
TRIP6
TRO
TTLL10
TYK2
TYMSOS
UBE2I
UBE2Q1
WNK1
YPEL3
ZNF417
ZNF512B
ZNRD1
Entrez ID
84708
2275
HPRD ID
17287
09101
Ensembl ID
ENSG00000072201
ENSG00000183386
Uniprot IDs
Q8TBB1
Q13643
Q96C98
PDB IDs
3B76
1WYH
2CUQ
2EHE
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
RNA Metabolic Process
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
SMAD Protein Complex Assembly
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Cellular Process
Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Cellular Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cell Differentiation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Cell Proliferation
Negative Regulation Of RNA Biosynthetic Process
Tissue Development
Positive Regulation Of Cellular Metabolic Process
Cell Death
Death
Multicellular Organismal Homeostasis
Positive Regulation Of Epithelial To Mesenchymal Transition
Endoderm Development
Negative Regulation Of Cell Growth
Embryonic Organ Development
Positive Regulation Of Metabolic Process
Primary MiRNA Processing
Organ Development
Apoptotic Process
Tagcloud
?
accompanied
adhesion
anchorage
antiproliferative
arrest
b1
cip1
downregulated
g1
g2
half
implicated
interfering
knockdown
lim
marked
marker
member
mobility
p21
progression
regulator
sirna
suppressed
thereby
transduction
unclear
waf1
Tagcloud (Difference)
?
accompanied
adhesion
anchorage
antiproliferative
arrest
b1
cip1
downregulated
g1
g2
half
implicated
interfering
knockdown
lim
marked
marker
member
mobility
p21
progression
regulator
sirna
suppressed
thereby
transduction
unclear
waf1
Tagcloud (Intersection)
?