TLE1 and HES1

  • Number of citations of the paper that reports this interaction (PMID 8687460)
  • 36
  • Data Source:
  • HPRD (two hybrid, in vitro)

TLE1

HES1

Gene Name transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) hes family bHLH transcription factor 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 85 interactors: ANXA7 APH1A ARL3 ARL4D ATN1 BARHL1 BCL2L1 BID BTBD2 CCL18 CDK1 CDKN1A CDKN2C CELF3 CRCT1 CSNK2B CTNNB1 DAZAP2 DLEU1 EIF2S2 EN1 ERH ESRRG FOXA1 FOXA2 FOXA3 FOXG1 FUBP1 FXYD6 GADD45A GRB7 GSK3B GSTM4 HES1 HES6 HESX1 HHEX HLA-DQA1 HMGB1 HNF1A HSPE1 IL6ST KDM6A KIAA0408 LEF1 MORF4L2 MPHOSPH6 MSX1 MSX2 NKX2-5 NUDT21 PAFAH1B3 PAX9 PCDHA4 PEX2 PFN1 POLB POLE2 PRDM1 PSMD11 RAP1B RCC1 RNF10 RPA2 RUNX1 RUNX3 SAT1 SERPINB9 SIX1 SIX2 SIX3 SIX6 SMN1 SNRPG TCF3 TCF4 TK1 TLE2 TLX1 TLX2 TLX3 TSC22D1 UTY VENTX ZFP64 33 interactors: APCS APH1A ASGR2 CSNK1E FANCA FANCE FANCF FANCG FANCL FHL1 FOXG1 GAPDH HDAC6 HES6 HEY2 HMGB1 HMGCL ID1 ID2 ID3 ID4 JAK2 LTBR NR4A1 NUDT3 PRKCA PTK2 SIRT1 STAT3 TLE1 TLE2 UBQLN1 YWHAB
Entrez ID 7088 3280
HPRD ID 02557 00770
Ensembl ID ENSG00000196781 ENSG00000114315
Uniprot IDs Q04724 Q14469
PDB IDs 1GXR 2CE8 2CE9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activates  carcinogenesis  colony  contributed  contributes  deregulation  dramatically  dysregulation  enhancer  growing  hcc  hepatic  hepatitis  hepatocarcinogenesis  hepatocellular  immunodeficient  indicates  insights  kappa  largely  micrornas  mir  mirna  mirnas  transducin  tumorigenesis  untranslated  utr  whereby 
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  tumorigenesis  variable  viable 
Tagcloud (Difference) ?
activates  carcinogenesis  colony  contributed  contributes  deregulation  dramatically  dysregulation  enhancer  growing  hcc  hepatic  hepatitis  hepatocarcinogenesis  hepatocellular  immunodeficient  indicates  insights  kappa  largely  micrornas  mir  mirna  mirnas  transducin  untranslated  utr  whereby 
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  variable  viable 
Tagcloud (Intersection) ?
tumorigenesis