RBBP4 and TSSK3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RBBP4	TSSK3
Gene Name		retinoblastoma binding protein 4	testis-specific serine kinase 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Sin3 Complex NuRD Complex NURF Complex CAF-1 Complex ESC/E(Z) Complex Protein Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Protein Binding DNA-dependent ATPase Activity Nucleosomal DNA Binding Histone Binding Histone Deacetylase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Chromatin Organization Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Gene Expression Chromatin Assembly CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Regulation Of Cell Cycle	Protein Phosphorylation Multicellular Organismal Development Spermatogenesis Regulation Of Signal Transduction Cell Differentiation
Pathways		Chromosome Maintenance Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Epigenetic regulation of gene expression G2/M Transition G0 and Early G1 PRC2 methylates histones and DNA Cell Cycle, Mitotic Chromatin modifying enzymes Nucleosome assembly Oxidative Stress Induced Senescence Mitotic G2-G2/M phases Mitotic G1-G1/S phases Polo-like kinase mediated events
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: AEBP2 ANXA7 BCL11B BRCA1 BRMS1 BRMS1L CDKN1A CHAF1B CREB1 CREBBP DHX30 EED ESR1 EZH2 GATAD2B HAT1 HDAC1 HDAC2 HDAC3 HDAC4 HIST1H1A HIST2H2AC HIST2H3C HIST2H4A HIST3H3 HMOX2 ING1 LINC00152 LMNA MBD2 MBD3 MBD3L2 MTA1 MTA2 NR2E3 RB1 RBBP7 RBP1 RPN1 RPN2 SAP30 SIN3A SMN1 SP1 SP3 SPEN SUV39H1 TK1 TSSK3 XRCC6	18 interactors: ADAMTSL4 AES C15orf48 EFHC2 FUT9 GOLGA2 GP2 IKZF3 LNX1 OIP5 RBBP4 RBCK1 REL SMAD4 TCF4 TRIM9 VPS52 ZBTB25
Entrez ID		5928	81629
HPRD ID		04232	09635
Ensembl ID		ENSG00000162521	ENSG00000162526
Uniprot IDs		Q09028	Q96PN8
PDB IDs		2XU7 3GFC
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Negative Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Organelle Organization Histone Modification Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Metabolic Process Chromatin Remodeling Histone Deacetylation Positive Regulation Of Transcription, DNA-templated Protein Deacetylation Biosynthetic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Rhythmic Process Chromatin Silencing Histone H3-K9 Modification Positive Regulation Of Metabolic Process Metabolic Process	Regulation Of Binding Regulation Of Cell Death Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Binding Protein-DNA Complex Assembly CENP-A Containing Nucleosome Assembly Positive Regulation Of Intracellular Protein Transport Cellular Macromolecule Biosynthetic Process Positive Regulation Of Epithelial To Mesenchymal Transition Macromolecule Biosynthetic Process Fucosylation Histone Exchange DNA Replication-independent Nucleosome Assembly Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Embryonic Digestive Tract Development RNA Biosynthetic Process Positive Regulation Of Intracellular Transport Centromere Complex Assembly Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Epithelial To Mesenchymal Transition Regulation Of Intracellular Protein Transport Positive Regulation Of Cell Death Cellular Macromolecular Complex Assembly Negative Regulation Of Protein Binding Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis ATP-dependent Chromatin Remodeling Somatic Stem Cell Maintenance Negative Regulation Of Gene Expression Positive Regulation Of Protein Transport Nephrogenic Mesenchyme Morphogenesis Negative Regulation Of SNARE Complex Assembly Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of BMP Signaling Pathway Biosynthetic Process Positive Regulation Of Protein Import Into Nucleus Regulation Of Apoptotic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Protein Linear Polyubiquitination Negative Regulation Of Binding Positive Regulation Of Protein Localization To Nucleus Maintenance Of DNA Repeat Elements
Tagcloud ?		bfls borjeson charged coregulator deacetylase disordered fog1 forssman gal4 homeodomain impair implicates insert lehmann lymphoblastic mta1 nucleosome nurd nurf55 overlaps pair phf6 pocket propeller recognizing remodeling repression su top
Tagcloud (Difference) ?		bfls borjeson charged coregulator deacetylase disordered fog1 forssman gal4 homeodomain impair implicates insert lehmann lymphoblastic mta1 nucleosome nurd nurf55 overlaps pair phf6 pocket propeller recognizing remodeling repression su top
Tagcloud (Intersection) ?