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FASLG and RGS20
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
FASLG
RGS20
Gene Name
Fas ligand (TNF superfamily, member 6)
regulator of G-protein signaling 20
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
External Side Of Plasma Membrane
Lysosomal Lumen
Perinuclear Region Of Cytoplasm
Cytoplasmic Membrane-bounded Vesicle Lumen
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Molecular Function
Receptor Binding
Death Receptor Binding
Cytokine Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
GTPase Activator Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Cell Apoptotic Process
Immune Response
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Cell Proliferation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Angiogenesis
Cellular Chloride Ion Homeostasis
Response To Lipopolysaccharide
Positive Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Retinal Cell Programmed Cell Death
Endosomal Lumen Acidification
T Cell Apoptotic Process
Necroptotic Process
Response To Growth Factor
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Necroptotic Signaling Pathway
Positive Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Pathways
Death Receptor Signalling
FasL/ CD95L signaling
Programmed Cell Death
Extrinsic Pathway
Signaling by GPCR
GPCR downstream signaling
G alpha (z) signalling events
G alpha (i) signalling events
Drugs
Diseases
GWAS
Celiac disease (
20190752
)
Crohn's disease (
21102463
23128233
)
Protein-Protein Interactions
74 interactors:
APBB1
ARHGAP9
BAIAP2L1
BTK
CACNB3
CACNB4
CRK
DAXX
DLG2
DMD
DNMBP
DOCK4
EPS8L3
EZR
FADD
FAS
FGR
FN1
FNBP1
FYB
FYN
GRAP
GRAP2
GRB2
HCK
ITK
ITSN2
KALRN
KMT2A
KRT40
LCK
LYN
MACC1
MIA
MMP7
MPP4
MYO15A
NCF1
NCK1
NCK2
NCKIPSD
NOTCH2NL
OSTF1
PACSIN2
PDCD6
PIK3CA
PIK3R1
PIN1
PPIAP11
PRPF40A
PSTPIP1
PTPN13
RGS20
RIMBP3C
SAMSN1
SH3GL3
SH3PXD2A
SH3PXD2B
SH3RF2
SKAP2
SNX33
SNX9
SORBS3
SPTA1
SRC
SRGAP1
SRGAP2
SRGAP3
SUMO1
TEC
TJP3
TNFRSF6B
TRIP6
YES1
33 interactors:
ADRB2
AQP1
CATSPER1
CRCT1
CREB5
FASLG
GLRX3
GNAI1
GNAI2
GNAI3
GNAO1
GNAZ
HOXA1
HSPD1
INS
KIF1A
KLHL38
KRTAP4-2
KRTAP5-6
KRTAP5-9
LCE1B
LCE2A
LCE2D
LCE3E
LCE4A
MAPKBP1
OSTM1
OTX1
PTGER3
PTPMT1
PVRL3
STMN2
TBC1D16
Entrez ID
356
8601
HPRD ID
00610
06225
Ensembl ID
ENSG00000117560
ENSG00000147509
Uniprot IDs
P48023
Q53ZZ1
H9NIM5
O76081
PDB IDs
1BZI
Enriched GO Terms of Interacting Partners
?
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Innate Immune Response
Immune System Process
Regulation Of Immune System Process
Regulation Of Cell Activation
Endocytosis
Positive Regulation Of Cell Activation
Immune Response
Regulation Of Cellular Process
T Cell Receptor Signaling Pathway
Axon Guidance
Regulation Of Lymphocyte Activation
Signal Transduction
Locomotion
Positive Regulation Of T Cell Activation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Positive Regulation Of Homotypic Cell-cell Adhesion
Defense Response
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell-cell Adhesion
Signaling
Regulation Of Signal Transduction
Cell Communication
Chemotaxis
T Cell Costimulation
Axonogenesis
Response To External Stimulus
Regulation Of T Cell Activation
Positive Regulation Of Cell Adhesion
Axon Development
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Metabolic Process
Vesicle-mediated Transport
Cell Morphogenesis Involved In Neuron Differentiation
Phagocytosis
Regulation Of Signaling
Cell Morphogenesis Involved In Differentiation
Cell Migration
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Keratinization
Keratinocyte Differentiation
Epidermis Development
Developmental Process
Epidermal Cell Differentiation
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Organ Development
System Development
Multicellular Organismal Development
Anatomical Structure Development
Skin Development
Heat Generation
G-protein Coupled Receptor Signaling Pathway
Cell Differentiation
Regulation Of Adenylate Cyclase Activity
Regulation Of Cyclase Activity
Tissue Development
Regulation Of CAMP Biosynthetic Process
Epithelium Development
Regulation Of CAMP Metabolic Process
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Epithelial Cell Differentiation
Temperature Homeostasis
Membrane Fusion
Regulation Of Body Fluid Levels
Cell-cell Signaling
Negative Regulation Of CAMP Biosynthetic Process
Sensory Organ Development
Wound Healing
Bicarbonate Transport
Negative Regulation Of CAMP Metabolic Process
Eye Morphogenesis
Cell Activation
Negative Regulation Of Nucleotide Metabolic Process
Acute-phase Response
Regulation Of Catalytic Activity
Response To Wounding
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
B Cell Cytokine Production
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Isotype Switching To IgG Isotypes
Anion Homeostasis
Tagcloud
?
casp3
cl
coincided
corpora
cyclic
disaggregation
estrous
extrinsic
fos
ifng
ifngamma
jun
lutea
luteal
luteolysis
luteolytic
p4
pgf2alpha
postmortem
pregnancy
proportions
tnfa
tnfr1
tnfr2
tnfrsf1a
tnfrsf1b
viable
Tagcloud (Difference)
?
casp3
cl
coincided
corpora
cyclic
disaggregation
estrous
extrinsic
fos
ifng
ifngamma
jun
lutea
luteal
luteolysis
luteolytic
p4
pgf2alpha
postmortem
pregnancy
proportions
tnfa
tnfr1
tnfr2
tnfrsf1a
tnfrsf1b
viable
Tagcloud (Intersection)
?