RBM8A and SF3B2

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM8A	SF3B2
Description		RNA binding motif protein 8A	splicing factor 3b subunit 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Dendrite Exon-exon Junction Complex Neuronal Cell Body U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Viral Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: APP CDC42 DPH1 EIF4A3 FBXO25 IKBKG IPO13 KAT2B MAGOH MAGOHB MCM7 NXF1 RNPS1 SF3B2 SRPK1 SRPK2 TCF12 TOE1 UPF3A UPF3B	103 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 HNRNPC KDM1A LSM2 LSM3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 PRC1 PRPF40A RBM10 RBM7 RBM8A SF3B4 SMAD3 SNRNP200 SUMO2 TCERG1 THOC1 TOE1 TOPBP1 TTC14 U2AF1 U2AF2 WBP4 ZCCHC10
Entrez ID		9939	10992
HPRD ID		05609	10410
Ensembl ID		ENSG00000265241	ENSG00000087365
Uniprot IDs		A0A023T787 Q9Y5S9	Q13435
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 5XJC 5YZG 6ICZ 6QDV 7A5P	2DO5 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6QX9 6Y50 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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