SF3B2 and C7orf25

Data Source:
BioGRID (two hybrid)

		SF3B2	C7orf25
Description		splicing factor 3b subunit 2	chromosome 7 open reading frame 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Viral Process
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)	Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)
Interacting Genes		103 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 HNRNPC KDM1A LSM2 LSM3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 PRC1 PRPF40A RBM10 RBM7 RBM8A SF3B4 SMAD3 SNRNP200 SUMO2 TCERG1 THOC1 TOE1 TOPBP1 TTC14 U2AF1 U2AF2 WBP4 ZCCHC10	20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1
Entrez ID		10992	79020
HPRD ID		10410	09861
Ensembl ID		ENSG00000087365	ENSG00000136197
Uniprot IDs		Q13435	Q9BPX7
PDB IDs		2DO5 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6QX9 6Y50 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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