RBM8A and DPH1

Data Source:
HPRD (two hybrid)

		RBM8A	DPH1
Description		RNA binding motif protein 8A	diphthamide biosynthesis 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Dendrite Exon-exon Junction Complex Neuronal Cell Body U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Cytosol Cell Junction
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Protein Binding Transferase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Diisocyanate-induced asthma ( 25918132) Hepatocyte growth factor levels ( 25998175) Itch intensity from mosquito bite ( 28199695)
Interacting Genes		20 interacting genes: APP CDC42 DPH1 EIF4A3 FBXO25 IKBKG IPO13 KAT2B MAGOH MAGOHB MCM7 NXF1 RNPS1 SF3B2 SRPK1 SRPK2 TCF12 TOE1 UPF3A UPF3B	4 interacting genes: HSPA5 RBM8A TFCP2 UBC
Entrez ID		9939	1801
HPRD ID		05609	04634
Ensembl ID		ENSG00000265241	ENSG00000108963
Uniprot IDs		A0A023T787 Q9Y5S9	Q9BZG8
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 5XJC 5YZG 6ICZ 6QDV 7A5P
Enriched GO Terms of Interacting Partners?
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