PAN2 and PAN3

Data Source:
HPRD (in vivo, in vitro)

		PAN2	PAN3
Description		poly(A) specific ribonuclease subunit PAN2	poly(A) specific ribonuclease subunit PAN3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol PAN Complex	P-body Cytosol PAN Complex
	Molecular Function	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding	RNA Binding Poly(A)-specific Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Proteolysis Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Protein Phosphopantetheinylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Protein Phosphorylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Deadenylation of mRNA	Deadenylation of mRNA
Drugs
Diseases
GWAS		Axial length ( 24144296) Height ( 25429064) Refractive error ( 32231278)	Bipolar disorder ( 20351715) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Hepcidin/transferrin saturation ratio ( 27846281) Mean corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		7 interacting genes: DYNLL1 PABPC1 PAN3 RBCK1 RNF144B TNRC6A TRIM35	4 interacting genes: PABPC1 PAN2 SVIL TNRC6B
Entrez ID		9924	255967
HPRD ID		15640	17818
Ensembl ID		ENSG00000135473	ENSG00000152520
Uniprot IDs		Q504Q3	Q58A45
PDB IDs
Enriched GO Terms of Interacting Partners?
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