TRANK1 and XIRP1

Data Source:
BioGRID (affinity chromatography technology)

		TRANK1	XIRP1
Description		tetratricopeptide repeat and ankyrin repeat containing 1	xin actin binding repeat containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Stress Fiber Focal Adhesion
	Molecular Function		RNA Binding Protein Binding Actin Filament Binding
	Biological Process		Actin Filament Organization Negative Regulation Of Protein Binding
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 22182935 28115744 24618891 31043756 28072414 27329760) Bipolar disorder with mood-incongruent psychosis ( 23092984) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Iris color (L* coordinate) ( 29109912) Mean platelet volume ( 32888494) Morning person ( 30696823) Platelet distribution width ( 27863252) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Schizophrenia or bipolar disorder ( 24280982) Subjective response to lithium treatment ( 26503763) Triglycerides ( 30275531)	Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)
Interacting Genes			8 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 VASP
Entrez ID		9881	165904
HPRD ID		19247	16727
Ensembl ID		ENSG00000168016	ENSG00000168334
Uniprot IDs		A0A2R8YEM9 O15050	Q702N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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