PLEKHM1 and MUC2

Data Source:
HPRD (in vitro)

		PLEKHM1	MUC2
Description		pleckstrin homology and RUN domain containing M1	mucin 2, oligomeric mucus/gel-forming
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Lysosomal Membrane Endosome Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Golgi Lumen Plasma Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Inner Mucus Layer Outer Mucus Layer
	Molecular Function	Metal Ion Binding	Protein Binding
	Biological Process	Autophagy Protein Transport Lysosome Localization Intracellular Signal Transduction Positive Regulation Of Bone Resorption Positive Regulation Of Ruffle Assembly	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Maintenance Of Gastrointestinal Epithelium
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 28093568) Epithelial ovarian cancer ( 25581431) Hip circumference ( 28552196) Male-pattern baldness ( 29146897 28196072) Neuroticism ( 29255261) Parkinson's disease ( 20070850) Remission after SSRI treatment in MDD or neuroticism ( 29559929)	Asthma ( 31361310 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Interstitial lung disease ( 23583980) Medication use (adrenergics, inhalants) ( 31015401)
Interacting Genes		9 interacting genes: BID EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9 TRIM54	4 interacting genes: GALNT12 GALNT14 MLH1 PLEKHM1
Entrez ID		9842	4583
HPRD ID		11439	11828
Ensembl ID		ENSG00000225190	ENSG00000198788
Uniprot IDs		Q9Y4G2
PDB IDs		5DPR 5DPS 5DPT 5DPW
Enriched GO Terms of Interacting Partners?
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