MUC2 and PLEKHM1

Data Source:
HPRD (in vitro)

		MUC2	PLEKHM1
Description		mucin 2, oligomeric mucus/gel-forming	pleckstrin homology and RUN domain containing M1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Lumen Plasma Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Inner Mucus Layer Outer Mucus Layer	Nucleolus Lysosomal Membrane Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Maintenance Of Gastrointestinal Epithelium	Autophagy Protein Transport Lysosome Localization Intracellular Signal Transduction Positive Regulation Of Bone Resorption Positive Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS		Asthma ( 31361310 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Interstitial lung disease ( 23583980) Medication use (adrenergics, inhalants) ( 31015401)	Alcohol use disorder (total score) ( 30336701) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 28093568) Epithelial ovarian cancer ( 25581431) Hip circumference ( 28552196) Male-pattern baldness ( 29146897 28196072) Neuroticism ( 29255261) Parkinson's disease ( 20070850) Remission after SSRI treatment in MDD or neuroticism ( 29559929)
Interacting Genes		4 interacting genes: GALNT12 GALNT14 MLH1 PLEKHM1	9 interacting genes: BID EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9 TRIM54
Entrez ID		4583	9842
HPRD ID		11828	11439
Ensembl ID		ENSG00000198788	ENSG00000225190
Uniprot IDs			Q9Y4G2
PDB IDs			5DPR 5DPS 5DPT 5DPW
Enriched GO Terms of Interacting Partners?
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