VPS9D1 and KRT35

Data Source:
BioGRID (two hybrid)

		VPS9D1	KRT35
Description		VPS9 domain containing 1	keratin 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	GTPase Activator Activity Transporter Activity Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	ATP Synthesis Coupled Proton Transport Positive Regulation Of GTPase Activity	Anatomical Structure Morphogenesis Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		25 interacting genes: AAMDC AHSP AKAP9 CCDC172 CCHCR1 DYDC1 FAM214B HOMEZ KRT31 KRT35 KRT39 MAP1LC3A MKRN3 PNMA1 POU6F2 PSMD2 RAD51D RSPH14 SYT17 TRIM21 TRIM27 TRIM54 TTC23L UBXN11 ZNF655	87 interacting genes: ABI3 ATG9A BCAS2 C1orf109 C21orf58 CCDC120 CCDC185 CCDC196 CCHCR1 CD33 CTSZ DMRT3 DTNB EFCAB3 ENKD1 EXOSC5 FAM221B FRS3 HAPLN2 HCK HDAC4 HGS HOXA1 HOXC8 KCTD9 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 LONRF1 MAPKBP1 MCRS1 MYO15B OIP5 OTX1 PKN1 POU4F2 PRPF18 PRPF31 PRR35 RUNX1T1 SCNM1 SHC3 SLC43A2 SMARCE1 SMYD1 TAPBPL TBC1D21 TBC1D30 TBC1D7 TCEANC TCHP TEKT4 TEPSIN TLE5 TRIM29 TSG101 TXLNA TXLNB UBASH3A USP2 VPS9D1 ZNF417 ZNF446
Entrez ID		9605	3886
HPRD ID		08508	04138
Ensembl ID		ENSG00000075399	ENSG00000197079
Uniprot IDs		Q9Y2B5	Q92764
PDB IDs
Enriched GO Terms of Interacting Partners?
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