RBM39 and THAP1

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM39	THAP1
Description		RNA binding motif protein 39	THAP domain containing 1
Image
GO Annotations	Cellular Component	Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite	Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding RS Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding
	Biological Process	RNA Processing MRNA Processing RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Blood protein levels ( 28240269) Refractive error ( 32231278)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		60 interacting genes: AK8 APP ARL6IP4 BANP CDC42 CHERP CLK1 CLK2 CSNK2A1 CSNK2B DARS1-AS1 DDX39B DVL3 ESR1 ESR2 FAM200A GOLGA2 H1-2 HNRNPH2 HOMEZ HSPB1 INO80B JUN KHDC4 KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 PGR PHC2 POU6F2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1 SREK1IP1 SRPK1 SRPK2 SRRM4 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10	105 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BEND7 BMS1P1 BYSL C1orf216 C1orf35 C4orf45 C7orf50 CDC37 CDKN2D CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FAM9A FGF10 FGF11 FGF12 FXR2 GAS8 GPATCH2L HNRNPLL HYPK INO80B KANK2 KLF12 KRTAP10-7 L3MBTL2 LASP1 LMNB2 LMO3 LNX1 MFAP1 MIS18A MORF4L1 MORF4L2 MRPL11 MRPL53 NDUFAB1 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PHF19 PID1 PNKP POLR2L POLR2M POU6F2 PPIG PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAD54L2 RALY RALYL RBM10 RBM39 RIPPLY1 RNF4 RP9P RPL22 RPS25 SAP30BP SERF2 SLU7 SPANXN2 SREK1IP1 STRBP TCEA2 TCEANC TPM3 TRAF5 TRIM26 TRIP10 TTLL10 TXN2 U2AF2 UBE2I VCX2 WT1 YES1 ZBTB48 ZCCHC10 ZGPAT ZNF385C ZNF408 ZNF526
Entrez ID		9584	55145
HPRD ID		09201	15496
Ensembl ID		ENSG00000131051	ENSG00000131931
Uniprot IDs		A0A384NQ03 B4DRA0 E1P5S2 Q14498 Q6N037	Q9NVV9
PDB IDs		2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5	2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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