GTF2IRD1 and DCAF6

Data Source:
BioGRID (two hybrid)

		GTF2IRD1	DCAF6
Description		GTF2I repeat domain containing 1	DDB1 and CUL4 associated factor 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber	Protein Ubiquitination Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Neddylation
Drugs
Diseases
GWAS		Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)	Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Schizophrenia ( 22037555)
Interacting Genes		24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5	13 interacting genes: ACVR1 AR BMPR1B CLIP4 CUL4A GTF2IRD1 MDFI NR3C1 SMAD2 SUPT5H TGFBR1 TRIM55 TRIM63
Entrez ID		9569	55827
HPRD ID		08379	17156
Ensembl ID		ENSG00000006704	ENSG00000143164
Uniprot IDs		E9PFE2 Q9UHL9	Q58WW2
PDB IDs		2D99 2DN5 2DZQ 2DZR	3I7O
Enriched GO Terms of Interacting Partners?
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