GTF2IRD1 and HTRA4

Data Source:
BioGRID (two hybrid)

		GTF2IRD1	HTRA4
Description		GTF2I repeat domain containing 1	HtrA serine peptidase 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Extracellular Region
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Insulin-like Growth Factor Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber	Proteolysis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469) Triglyceride levels ( 32203549)
Interacting Genes		24 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 GORASP2 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 MRFAP1L1 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5	1 interacting genes: GTF2IRD1
Entrez ID		9569	203100
HPRD ID		08379	08818
Ensembl ID		ENSG00000006704	ENSG00000169495
Uniprot IDs		E9PFE2 Q9UHL9	P83105
PDB IDs		2D99 2DN5 2DZQ 2DZR
Enriched GO Terms of Interacting Partners?
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