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POLR1C and KRTAP12-2
Data Source:
BioGRID
(two hybrid)
POLR1C
KRTAP12-2
Description
RNA polymerase I and III subunit C
keratin associated protein 12-2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
RNA Polymerase III Complex
RNA Polymerase I Complex
Cytosol
Cytosol
Keratin Filament
Molecular Function
RNA Polymerase I Activity
RNA Polymerase III Activity
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
Protein Binding
Biological Process
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase III
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Gene Expression, Epigenetic
Keratinization
Pathways
Cytosolic sensors of pathogen-associated DNA
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Keratinization
Drugs
Diseases
Treacher Collins syndrome
GWAS
GLP-1 levels in response to oral glucose tolerance test (fasting) (
29093273
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
119 interacting genes:
ADAMTSL4
ARHGEF5
ATRIP
AVPI1
BHLHB9
BIN3
BIRC7
BLZF1
C1orf105
C21orf58
C4orf45
CBX8
CBY2
CCDC33
CCNK
CCT3
CGGBP1
CLU
CORO1A
CORO1B
CRACR2A
EFHC2
EP400
FH
FMR1
FOXR2
GAS8
GMPPB
GOLGA6A
GOLGA6L9
GRPEL1
GSTO2
HDX
HNRNPH1
HOXB9
HOXD12
IHO1
IKZF3
INCA1
KCTD1
KCTD13
KLF15
KRT19
KRT75
KRT76
KRTAP12-2
KRTAP3-1
LNX2
LRIF1
LZTS1
LZTS2
MBIP
MEI4
MEOX2
MKRN3
MORN3
MRPS23
MYD88
MYO5B
NDUFB10
NEDD4
NFKBIB
NIF3L1
NME1
NME4
PIH1D2
POLDIP3
POLR1D
POLR1E
POLR1G
POLR2G
POLR2J
POLR2J3
PPP2R3C
PSMA1
RBM48
RIMBP3
RIMBP3C
RSPH14
RUSC1
SAXO1
SMN1
SMN2
SORBS3
SPATC1L
SPRY1
STMN3
TASOR2
TAX1BP1
TCF4
TEX43
TFIP11
TLE5
TMEM121
TNFAIP1
TNNI1
TRAIP
TRIM14
TRIM27
TRIOBP
TSC22D4
UNKL
USP54
VIM
WASHC1
WRN
XPA
YPEL3
ZBED1
ZBTB42
ZC2HC1C
ZFP57
ZIM2
ZNF547
ZNF554
ZNF655
ZNF688
ZNF835
ZRANB1
125 interacting genes:
ADAM12
ARID5A
ATN1
ATP6V1C2
AVPI1
BCL6B
BEX2
CATSPER1
CBLL2
CBX2
CCNL1
CCNL2
CFP
CHRD
CNNM3
CYSRT1
DGCR6
DHRS1
EFEMP2
ETNK2
FAM27E3
FHL3
FOXD4
FOXD4L1
FOXD4L3
GDF15
GPANK1
GPRIN2
GREM1
HOXA1
HOXB9
HSFX1
HSFX2
HYPK
INO80B
IQUB
KRT34
KRTAP10-5
KRTAP10-8
KRTAP12-1
KRTAP12-4
KRTAP13-2
KRTAP15-1
KRTAP19-2
KRTAP21-2
KRTAP26-1
KRTAP3-2
KRTAP4-2
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-3
KRTAP9-8
LCE1A
LCE1C
LCE1F
LCE2A
LCE2B
LCE4A
LINC00671
MEOX2
MGAT5B
MYOZ1
MYPOP
NBPF19
NECTIN2
NOTCH2NLA
NPDC1
NR1D2
ODF1
OTX1
PACSIN3
PATZ1
PCSK5
PDE9A
PELO
PHLDA1
PIH1D2
PLAC8
POLR1C
POM121L8P
POU4F2
RAD23A
RBM39
RBPMS
RBX1
RHOXF2
SEMA3B
SLC12A4
SLC13A5
SLC15A2
SLC15A3
SPATA3
SPRED2
SPRY1
SRSF8
TCEA2
TEX37
TINAGL1
TLE5
TMEM179B
TNS2
TRIM42
TRIP13
TSGA10IP
TTPA
VASN
VENTX
VGLL3
YIPF3
YY1
ZBTB9
ZDHHC1
ZIM2
ZNF100
ZNF408
ZNF497
ZNF581
ZNF587
ZNF624
ZNF688
ZNF696
ZNF764
ZNF785
ZNHIT1
Entrez ID
9533
353323
HPRD ID
09661
11198
Ensembl ID
ENSG00000171453
ENSG00000221864
Uniprot IDs
O15160
P59991
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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