KRTAP12-2 and PLAC8

Data Source:
BioGRID (two hybrid)

		KRTAP12-2	PLAC8
Description		keratin associated protein 12-2	placenta associated 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Extracellular Region Azurophil Granule Lumen
	Molecular Function	Protein Binding	Chromatin Binding
	Biological Process	Keratinization	Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis
Pathways		Keratinization	Neutrophil degranulation
Drugs
Diseases
GWAS			QRS interval (sulfonylurea treatment interaction) ( 27958378)
Interacting Genes		125 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1C LCE1F LCE2A LCE2B LCE4A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPRED2 SPRY1 SRSF8 TCEA2 TEX37 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1	24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX
Entrez ID		353323	51316
HPRD ID		11198	06335
Ensembl ID		ENSG00000221864	ENSG00000145287
Uniprot IDs		P59991	Q9NZF1 X2BQ60
PDB IDs
Enriched GO Terms of Interacting Partners?
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