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KRTAP12-2 and PELO
Data Source:
BioGRID
(two hybrid)
KRTAP12-2
PELO
Description
keratin associated protein 12-2
pelota mRNA surveillance and ribosome rescue factor
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Nucleus
Cytoplasm
Molecular Function
Protein Binding
Endonuclease Activity
Protein Binding
Metal Ion Binding
Biological Process
Keratinization
Inner Cell Mass Cell Proliferation
Cell Cycle
Endoderm Development
Stem Cell Population Maintenance
Positive Regulation Of BMP Signaling Pathway
Ribosome Disassembly
Chromosome Organization
Cell Division
Mesenchymal To Epithelial Transition
Nuclear-transcribed MRNA Catabolic Process, Non-stop Decay
Nonfunctional RRNA Decay
Nuclear-transcribed MRNA Catabolic Process, No-go Decay
RNA Surveillance
Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Keratinization
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Birth weight (
31043758
)
Diastolic blood pressure (
27841878
)
Heel bone mineral density (
30598549
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
27863252
)
Low density lipoprotein cholesterol levels (
32154731
)
Presence of antiphospholipid antibodies (
23509613
)
Response to platinum-based agents (
22020760
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Serum total protein level (
29403010
)
Systolic blood pressure (
27841878
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
125 interacting genes:
ADAM12
ARID5A
ATN1
ATP6V1C2
AVPI1
BCL6B
BEX2
CATSPER1
CBLL2
CBX2
CCNL1
CCNL2
CFP
CHRD
CNNM3
CYSRT1
DGCR6
DHRS1
EFEMP2
ETNK2
FAM27E3
FHL3
FOXD4
FOXD4L1
FOXD4L3
GDF15
GPANK1
GPRIN2
GREM1
HOXA1
HOXB9
HSFX1
HSFX2
HYPK
INO80B
IQUB
KRT34
KRTAP10-5
KRTAP10-8
KRTAP12-1
KRTAP12-4
KRTAP13-2
KRTAP15-1
KRTAP19-2
KRTAP21-2
KRTAP26-1
KRTAP3-2
KRTAP4-2
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-3
KRTAP9-8
LCE1A
LCE1C
LCE1F
LCE2A
LCE2B
LCE4A
LINC00671
MEOX2
MGAT5B
MYOZ1
MYPOP
NBPF19
NECTIN2
NOTCH2NLA
NPDC1
NR1D2
ODF1
OTX1
PACSIN3
PATZ1
PCSK5
PDE9A
PELO
PHLDA1
PIH1D2
PLAC8
POLR1C
POM121L8P
POU4F2
RAD23A
RBM39
RBPMS
RBX1
RHOXF2
SEMA3B
SLC12A4
SLC13A5
SLC15A2
SLC15A3
SPATA3
SPRED2
SPRY1
SRSF8
TCEA2
TEX37
TINAGL1
TLE5
TMEM179B
TNS2
TRIM42
TRIP13
TSGA10IP
TTPA
VASN
VENTX
VGLL3
YIPF3
YY1
ZBTB9
ZDHHC1
ZIM2
ZNF100
ZNF408
ZNF497
ZNF581
ZNF587
ZNF624
ZNF688
ZNF696
ZNF764
ZNF785
ZNHIT1
13 interacting genes:
DYNLT1
FLNA
HBS1L
HSPB1
KRTAP12-2
LMO3
LMO4
MEOX2
PIK3R3
PRMT6
PTEN
TRIM55
TRIM63
Entrez ID
353323
53918
HPRD ID
11198
09309
Ensembl ID
ENSG00000221864
ENSG00000152684
Uniprot IDs
P59991
Q9BRX2
PDB IDs
1X52
5EO3
5LZW
5LZX
5LZY
5LZZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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