PMPCB and AP4M1

Data Source:
BioGRID (affinity chromatography technology)

		PMPCB	AP4M1
Description		peptidase, mitochondrial processing subunit beta	adaptor related protein complex 4 subunit mu 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Metal Ion Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Mitochondrial protein import Processing of SMDT1	Lysosome Vesicle Biogenesis
Drugs
Diseases			Cerebral palsy
GWAS		Diverticular disease ( 30177863)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: FXN MARK3 NPSR1 PMPCA PTGER4	14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		9512	9179
HPRD ID		07539	03803
Ensembl ID		ENSG00000105819	ENSG00000221838
Uniprot IDs		B3KM34 O75439 Q96CP5	C9JC87 O00189
PDB IDs			3L81 4MDR
Enriched GO Terms of Interacting Partners?
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