AP4M1 and TGOLN2

Data Source:
HPRD (in vitro)

		AP4M1	TGOLN2
Description		adaptor related protein complex 4 subunit mu 1	trans-golgi network protein 2
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GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleoplasm Endosome Endoplasmic Reticulum Lumen Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Transport Vesicle Trans-Golgi Network Transport Vesicle Clathrin-coated Vesicle Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Post-translational Protein Modification Cellular Protein Metabolic Process Membrane Organization
Pathways		Lysosome Vesicle Biogenesis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Golgi Associated Vesicle Biogenesis Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Post-translational protein phosphorylation
Drugs
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	10 interacting genes: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2
Entrez ID		9179	10618
HPRD ID		03803	04343
Ensembl ID		ENSG00000221838	ENSG00000152291
Uniprot IDs		C9JC87 O00189	O43493
PDB IDs		3L81 4MDR	6YAF
Enriched GO Terms of Interacting Partners?
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