AP4M1 and CACNG3

Data Source:
HPRD (two hybrid)

		AP4M1	CACNG3
Description		adaptor related protein complex 4 subunit mu 1	calcium voltage-gated channel auxiliary subunit gamma 3
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Plasma Membrane Voltage-gated Calcium Channel Complex Dendrite Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Somatodendritic Compartment Excitatory Synapse Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding	Voltage-gated Calcium Channel Activity Channel Regulator Activity PDZ Domain Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Protein Targeting Calcium Ion Transport Protein Localization Transmission Of Nerve Impulse Positive Regulation Of Synaptic Transmission, Glutamatergic Cardiac Conduction Calcium Ion Transmembrane Transport Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Postsynaptic Neurotransmitter Receptor Diffusion Trapping Neurotransmitter Receptor Internalization Regulation Of AMPA Receptor Activity Positive Regulation Of AMPA Receptor Activity
Pathways		Lysosome Vesicle Biogenesis	Trafficking of AMPA receptors LGI-ADAM interactions
Drugs			Ergocalciferol Enflurane Spironolactone Butamben Bioallethrin
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Chronotype ( 30696823) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	2 interacting genes: AP4M1 APP
Entrez ID		9179	10368
HPRD ID		03803	05910
Ensembl ID		ENSG00000221838	ENSG00000006116
Uniprot IDs		C9JC87 O00189	O60359
PDB IDs		3L81 4MDR
Enriched GO Terms of Interacting Partners?
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