MED20 and CYB5R2

Data Source:
BioGRID (two hybrid)

		MED20	CYB5R2
Description		mediator complex subunit 20	cytochrome b5 reductase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex	Nucleus Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding FAD Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated	Bicarbonate Transport Sterol Biosynthetic Process
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Erythrocytes take up carbon dioxide and release oxygen
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978 27863252) Mean corpuscular volume ( 23263863 20139978 27863252) Metabolite levels ( 23823483) Red blood cell count ( 20139978)	Blood pressure ( 23972371) Malaria ( 31844061) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: ANKS1A CD300C CYB5R2 ERP27 ESR1 ESR2 GABPB1 MARK4 MED18 MED29 MED8 PIH1D2 POLR1B PSORS1C2 TRIM69 YY1	20 interacting genes: AGR2 CDC23 COIL FANCL FFAR2 GOLGA2 HGS MED20 MEOX2 NFKBID PSMC6 REL SUOX TRAF1 TRAF2 TRIM55 TRIM63 TRIP13 YPEL3 ZNF778
Entrez ID		9477	51700
HPRD ID		15638	06435
Ensembl ID		ENSG00000124641	ENSG00000166394
Uniprot IDs		B3KUJ9 Q9H944	A8K237 Q6BCY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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