CYB5R2 and MED20

Data Source:
BioGRID (two hybrid)

		CYB5R2	MED20
Description		cytochrome b5 reductase 2	mediator complex subunit 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Membrane	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding FAD Binding	Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Bicarbonate Transport Sterol Biosynthetic Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways		Erythrocytes take up carbon dioxide and release oxygen	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Blood pressure ( 23972371) Malaria ( 31844061) Metabolite levels ( 23823483)	Mean corpuscular hemoglobin ( 20139978 27863252) Mean corpuscular volume ( 23263863 20139978 27863252) Metabolite levels ( 23823483) Red blood cell count ( 20139978)
Interacting Genes		20 interacting genes: AGR2 CDC23 COIL FANCL FFAR2 GOLGA2 HGS MED20 MEOX2 NFKBID PSMC6 REL SUOX TRAF1 TRAF2 TRIM55 TRIM63 TRIP13 YPEL3 ZNF778	16 interacting genes: ANKS1A CD300C CYB5R2 ERP27 ESR1 ESR2 GABPB1 MARK4 MED18 MED29 MED8 PIH1D2 POLR1B PSORS1C2 TRIM69 YY1
Entrez ID		51700	9477
HPRD ID		06435	15638
Ensembl ID		ENSG00000166394	ENSG00000124641
Uniprot IDs		A8K237 Q6BCY4	B3KUJ9 Q9H944
PDB IDs
Enriched GO Terms of Interacting Partners?
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