MED20 and ERP27

Data Source:
BioGRID (two hybrid)

		MED20	ERP27
Description		mediator complex subunit 20	endoplasmic reticulum protein 27
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated	Protein Folding Response To Unfolded Protein Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978 27863252) Mean corpuscular volume ( 23263863 20139978 27863252) Metabolite levels ( 23823483) Red blood cell count ( 20139978)	Hand grip strength ( 29313844) Osteoarthritis of the hand ( 28855172)
Interacting Genes		16 interacting genes: ANKS1A CD300C CYB5R2 ERP27 ESR1 ESR2 GABPB1 MARK4 MED18 MED29 MED8 PIH1D2 POLR1B PSORS1C2 TRIM69 YY1	11 interacting genes: BLOC1S2 C12orf60 EEF1D GOLGA8F MED20 PDIA3 SGTA UBL4A UBQLN1 UBQLN2 UBQLN4
Entrez ID		9477	121506
HPRD ID		15638	08723
Ensembl ID		ENSG00000124641	ENSG00000139055
Uniprot IDs		B3KUJ9 Q9H944	F5GYS6 Q96DN0
PDB IDs			2L4C 4F9Z
Enriched GO Terms of Interacting Partners?
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