PCYT1B and ACTA2

Data Source:
HPRD (in vitro)

		PCYT1B	ACTA2
Description		phosphate cytidylyltransferase 1, choline, beta	actin alpha 2, smooth muscle
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Extracellular Space Cytoplasm Cytosol Dynactin Complex Lamellipodium Filopodium Smooth Muscle Contractile Fiber Protein-containing Complex Cell Body Extracellular Exosome
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity Phosphatidylcholine Binding	ATP Binding Protein Kinase Binding
	Biological Process	Ovarian Follicle Development Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Spermatogenesis	Muscle Contraction Regulation Of Blood Pressure Response To Virus Positive Regulation Of Gene Expression Vascular Associated Smooth Muscle Contraction Positive Regulation Of Transcription, DNA-templated Glomerular Mesangial Cell Development Mesenchyme Migration
Pathways		Synthesis of PC	Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription
Drugs		Choline Choline salicylate	Phenethyl Isothiocyanate
Diseases			Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS			Arthritis (juvenile idiopathic) ( 33106285) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia ( 26956414 23770605) Immunoglobulin A ( 20694011) Lymphocyte percentage of white cells ( 32888494) Pulse pressure ( 30578418) Selective IgA deficiency ( 27723758)
Interacting Genes		8 interacting genes: ACTA1 ACTA2 APP ECPAS PAXIP1 PCYT1A TMEM43 VKORC1L1	18 interacting genes: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SELE SHBG SNTA1 TMSB4X UBE3A YBX1
Entrez ID		9468	59
HPRD ID		05376	00031
Ensembl ID		ENSG00000102230	ENSG00000107796
Uniprot IDs		Q9Y5K3	D2JYH4 P62736
PDB IDs
Enriched GO Terms of Interacting Partners?
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