FBXO44 and BLOC1S1

Data Source:
BioGRID (two hybrid)

		FBXO44	BLOC1S1
Description		F-box protein 44	biogenesis of lysosomal organelles complex 1 subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)	Refractive error ( 32231278)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 C11orf45 HSF2BP ISY1-RAB43 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	18 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 DCTN2 FBXO44 HGS MAGEB4 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPC5 SNAPIN USHBP1
Entrez ID		93611	2647
HPRD ID		16445	03263
Ensembl ID		ENSG00000132879	ENSG00000135441
Uniprot IDs		A0A024R4F9 A0A024R4J6 B7Z1P2 Q9H4M3	P78537
PDB IDs		3WSO 5B4N
Enriched GO Terms of Interacting Partners?
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