FBXO44 and ISY1-RAB43

Data Source:
BioGRID (two hybrid)

		FBXO44	ISY1-RAB43
Description		F-box protein 44	ISY1-RAB43 readthrough
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GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 C11orf45 HSF2BP ISY1-RAB43 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	14 interacting genes: CCDC185 EXOC8 FAM161B FARS2 FBXO44 FRS3 LENG1 NME7 NXF1 RCOR3 TSTD2 UBASH3A ZNF587 ZNF629
Entrez ID		93611	100534599
HPRD ID		16445
Ensembl ID		ENSG00000132879	ENSG00000261796
Uniprot IDs		A0A024R4F9 A0A024R4J6 B7Z1P2 Q9H4M3	Q9ULR0
PDB IDs		3WSO 5B4N	5YZG 6FF7 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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