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EFTUD2 and CYFIP1
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
EFTUD2
CYFIP1
Description
elongation factor Tu GTP binding domain containing 2
cytoplasmic FMR1 interacting protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Cajal Body
Membrane
Nuclear Speck
Intracellular Membrane-bounded Organelle
U4/U6 X U5 Tri-snRNP Complex
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 2 Spliceosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Ruffle
Extracellular Region
Cytosol
MRNA Cap Binding Complex
Focal Adhesion
Lamellipodium
SCAR Complex
Filopodium Tip
Secretory Granule Lumen
Specific Granule Lumen
Neuron Projection
Neuronal Cell Body
Terminal Bouton
Dendritic Spine
Dendritic Growth Cone
Axonal Growth Cone
Synapse
Perinuclear Region Of Cytoplasm
Excitatory Synapse
Extracellular Exosome
Central Region Of Growth Cone
Peripheral Region Of Growth Cone
Tertiary Granule Lumen
Molecular Function
RNA Binding
GTPase Activity
Protein Binding
GTP Binding
U5 SnRNA Binding
RNA 7-methylguanosine Cap Binding
Protein Binding
Small GTPase Binding
Translation Regulator Activity
Actin Filament Binding
Biological Process
MRNA Splicing, Via Spliceosome
Cellular Response To Drug
Response To Cocaine
Cell Morphogenesis
Regulation Of Translation
Axon Guidance
Regulation Of Cell Shape
Positive Regulation Of Lamellipodium Assembly
Rac Protein Signal Transduction
Cell Projection Assembly
Lamellipodium Assembly
Ruffle Organization
Regulation Of Myelination
Cellular Response To Insulin Stimulus
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Neutrophil Degranulation
Positive Regulation Of Axon Extension
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Axon Extension
Cognition
Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Response To Electrical Stimulus
Dendrite Extension
Modification Of Synaptic Structure
Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission
Positive Regulation Of Dendrite Development
Positive Regulation Of Ruffle Assembly
Negative Regulation Of Synaptic Vesicle Recycling
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Neutrophil degranulation
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Asthma (
31619474
)
Craniofacial microsomia (
26853712
)
Heel bone mineral density (
30598549
)
Platelet distribution width (
32888494
)
Triglyceride levels x loop diuretics use interaction (
31806883
)
World class endurance athleticism (
32612638
)
Interacting Genes
14 interacting genes:
ARPC3
CYFIP1
DUX4
GOLM1
GSK3B
HINFP
LSM8
PIN1
SF3B3
SF3B4
SNRNP200
SREK1
SUMO2
WBP4
18 interacting genes:
ACTA1
APBB1
EFHC2
EFTUD2
FMR1
FXR2
GAS7
GNB1
MEOX1
MYO16
NYAP1
NYAP2
PPP1CC
PRPF40A
RAC1
RFX6
SCTR
TCERG1
Entrez ID
9343
23191
HPRD ID
04869
05890
Ensembl ID
ENSG00000108883
ENSG00000273749
Uniprot IDs
B3KX19
Q15029
Q7L576
PDB IDs
3JCR
5MQF
5O9Z
5XJC
5YZG
5Z56
5Z57
5Z58
6AH0
6AHD
6FF4
6FF7
6ICZ
6ID0
6ID1
6QDV
6QW6
6QX9
6ZYM
3P8C
4N78
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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