EFTUD2 and SNRNP200

Data Source:
BioGRID (two hybrid)

		EFTUD2	SNRNP200
Description		elongation factor Tu GTP binding domain containing 2	small nuclear ribonucleoprotein U5 subunit 200
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Asthma ( 31619474) Craniofacial microsomia ( 26853712)
Interacting Genes		14 interacting genes: ARPC3 CYFIP1 DUX4 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 SUMO2 WBP4	34 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B DHX38 DUX4 ECT2 EFTUD2 ERG GNMT GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PRPF8 PTEN RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 SUMO2 UBE2I USP19 WBP4 YWHAB YWHAG
Entrez ID		9343	23020
HPRD ID		04869	03391
Ensembl ID		ENSG00000108883	ENSG00000144028
Uniprot IDs		B3KX19 Q15029	O75643
PDB IDs		3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6ZYM	2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9 6S8O 6S8Q 6S9I 7A5P
Enriched GO Terms of Interacting Partners?
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