SNAP29 and VAMP4

Data Source:
BioGRID (two hybrid)

		SNAP29	VAMP4
Description		synaptosome associated protein 29	vesicle associated membrane protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse	Golgi Membrane Lysosome Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Synaptic Vesicle Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation	Microtubule Cytoskeleton Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis
Pathways		Neutrophil degranulation Intra-Golgi traffic	Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS			Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		34 interacting genes: AP2A1 ATF4 CD7 COG6 DNAJC5 EHD1 EHD3 FAM9B FAM9C ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX16 STX17 STX1A STX1B STX2 STX3 STX4 STX6 STX7 TRAF3 TSNARE1 TXNRD3 VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7	45 interacting genes: ANKS6 AP1M1 AQP6 ARL13B BCL2L13 CISD2 CPLX4 CSNK2A1 CYB5R3 DNAJC5 EBP ELOVL4 ERGIC3 EVI2B FAM209A FAM210B GPR152 GPX8 KASH5 LDLRAD1 LEUTX MFF MGST3 MTIF3 PACS1 PSCA PTGES REEP4 RETREG3 SAR1A SEC11C SLC10A6 SNAP29 SSMEM1 STOM STX16 STX1A STX4 STX6 SYT2 TM4SF19 TMEM205 TMEM51 TMX2 TRIM54
Entrez ID		9342	8674
HPRD ID		11968	06070
Ensembl ID		ENSG00000099940	ENSG00000117533
Uniprot IDs		O95721	O75379 Q6IAZ3
PDB IDs		4WY4 7BV6
Enriched GO Terms of Interacting Partners?
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