SNAP29 and ITSN2

Data Source:
BioGRID (two hybrid)

		SNAP29	ITSN2
Description		synaptosome associated protein 29	intersectin 2
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse	Cytoplasm Centrosome Plasma Membrane Clathrin-coated Pit Presynaptic Membrane Extracellular Exosome Intracellular Vesicle Presynapse
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation	Endocytosis Viral Process Endosomal Transport Cell Differentiation Regulation Of Catalytic Activity Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Dendrite Extension
Pathways		Neutrophil degranulation Intra-Golgi traffic	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases		Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS			Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Low density lipoprotein cholesterol levels ( 32154731) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		34 interacting genes: AP2A1 ATF4 CD7 COG6 DNAJC5 EHD1 EHD3 FAM9B FAM9C ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX16 STX17 STX1A STX1B STX2 STX3 STX4 STX6 STX7 TRAF3 TSNARE1 TXNRD3 VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7	75 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1
Entrez ID		9342	50618
HPRD ID		11968	09193
Ensembl ID		ENSG00000099940	ENSG00000198399
Uniprot IDs		O95721	A6H8W8 Q9NZM3
PDB IDs		4WY4 7BV6	1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO
Enriched GO Terms of Interacting Partners?
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