GPR37L1 and TMEM54

Data Source:
BioGRID (two hybrid)

		GPR37L1	TMEM54
Description		G protein-coupled receptor 37 like 1	transmembrane protein 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Biological_process
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B	24 interacting genes: ARL13B CD3G CLSTN3 CREB3 FKBP7 GPR152 GPR37L1 KCNJ8 KCNK5 KLRC1 LMNA MS4A14 NRG1 PEX19 PSCA PVR RBBP8 SERINC2 SLC12A7 SLC39A2 TIMMDC1 TMEM52B TSPO2 UPK1B
Entrez ID		9283	113452
HPRD ID		13603	12524
Ensembl ID		ENSG00000170075	ENSG00000121900
Uniprot IDs		O60883	Q969K7
PDB IDs
Enriched GO Terms of Interacting Partners?
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