GPR37L1 and ADGRB3

Data Source:
BioGRID (two hybrid)

		GPR37L1	ADGRB3
Description		G protein-coupled receptor 37 like 1	adhesion G protein-coupled receptor B3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Synaptic Cleft Postsynapse
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding	G Protein-coupled Receptor Activity GTPase Activator Activity Protein Binding
	Biological Process	Negative Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Myoblast Fusion Neuron Remodeling Negative Regulation Of Angiogenesis Positive Regulation Of GTPase Activity Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Motor Learning Maintenance Of Synapse Structure
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)	General risk tolerance (MTAG) ( 30643258) Negative urgency ( 30718321) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes		52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B	8 interacting genes: C1QL3 ELMO1 GPATCH11 GPR37L1 MUC1 SLC7A1 SNTA1 TLCD4
Entrez ID		9283	577
HPRD ID		13603	04064
Ensembl ID		ENSG00000170075	ENSG00000135298
Uniprot IDs		O60883	O60242
PDB IDs			4DLO
Enriched GO Terms of Interacting Partners?
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