CYTH2 and INAVA

Data Source:
BioGRID (pull down)

		CYTH2	INAVA
Description		cytohesin 2	innate immunity activator
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone	Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding
	Biological Process	Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	Activation Of MAPK Activity Pattern Recognition Receptor Signaling Pathway Cytokine Production Involved In Immune Response Positive Regulation Of Protein Ubiquitination Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Adherens Junction Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Intestinal Epithelial Structure Maintenance Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Reactive Oxygen Species Biosynthetic Process
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Formic acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A
Diseases
GWAS		Abstraction and mental flexibility ( 31596458)	Celiac disease ( 30572963)
Interacting Genes		31 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CNKSR1 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 PIK3CA PNPLA2 PRKCA PRKCB PRKCG TCIRG1 TRIM23	3 interacting genes: CYTH1 CYTH2 CYTH3
Entrez ID		9266	55765
HPRD ID		03925	07712
Ensembl ID		ENSG00000105443	ENSG00000163362
Uniprot IDs		Q99418	Q3KP66
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21
Enriched GO Terms of Interacting Partners?
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