INAVA and CYTH1

Data Source:
BioGRID (pull down)

		INAVA	CYTH1
Description		innate immunity activator	cytohesin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Activation Of MAPK Activity Pattern Recognition Receptor Signaling Pathway Cytokine Production Involved In Immune Response Positive Regulation Of Protein Ubiquitination Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Adherens Junction Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Intestinal Epithelial Structure Maintenance Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Reactive Oxygen Species Biosynthetic Process	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs
Diseases
GWAS		Celiac disease ( 30572963)	Anxiety and major depressive disorder ( 24047446) Atrial fibrillation ( 30061737) HDL cholesterol levels ( 32203549) Pulse pressure ( 27841878 30578418) Red cell distribution width ( 32888494) Systolic blood pressure ( 27841878)
Interacting Genes		3 interacting genes: CYTH1 CYTH2 CYTH3	16 interacting genes: ACTA1 ARF1 ARF6 ARFRP1 CCDC120 CNKSR1 CYTIP FOSL2 GNAQ INAVA IPCEF1 ITGB2 ITSN1 PRKCD SNAPC5 TRIM23
Entrez ID		55765	9267
HPRD ID		07712	01630
Ensembl ID		ENSG00000163362	ENSG00000108669
Uniprot IDs		Q3KP66	B7Z9W0 Q15438
PDB IDs			1BC9 4A4P
Enriched GO Terms of Interacting Partners?
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