CYTH3 and FRMD4B

Data Source:
HPRD (in vivo)

		CYTH3	FRMD4B
Description		cytohesin 3	FERM domain containing 4B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Ruffle Extracellular Space Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity	Establishment Of Epithelial Cell Polarity
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)	Atrial fibrillation ( 30061737) Carotid intima media thickness x smoking interaction ( 32117412) Celiac disease ( 20190752 31591516) Fast beta electroencephalogram ( 28040410) Hepcidin/ferritin ratio ( 27846281) High myopia ( 32428537) PR interval ( 30046033 32439900) Renal underexcretion gout ( 32238385) Resting heart rate ( 27798624) Resting-state electroencephalogram vigilance ( 29703947) Sphingomyelin 24:0 levels ( 31560688) Trunk fat mass ( 28552196)
Interacting Genes		12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN	1 interacting genes: CYTH3
Entrez ID		9265	23150
HPRD ID		05469	19415
Ensembl ID		ENSG00000008256	ENSG00000114541
Uniprot IDs		O43739	B3KNA2 E9PGA7 Q6PEW6 Q9Y2L6
PDB IDs		4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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