CD8B and CD8A

Data Source:
BioGRID (imaging technique)
HPRD (in vivo, in vitro)

		CD8B	CD8A
Description		CD8b molecule	CD8a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Early Endosome Membrane T Cell Receptor Complex	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane T Cell Receptor Complex Plasma Membrane Raft
	Molecular Function	Protein Binding Coreceptor Activity MHC Class I Protein Binding	Protein Binding Coreceptor Activity MHC Class I Protein Complex Binding MHC Class I Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway T Cell Activation Regulation Of Defense Response To Virus By Virus Regulation Of Immune Response	T Cell Mediated Immunity Immune Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Antigen Processing And Presentation T Cell Activation Cytotoxic T Cell Differentiation Regulation Of Immune Response
Pathways		Nef Mediated CD8 Down-regulation Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases			Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Progressive supranuclear palsy ( 21685912)	Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: CD3D CD8A ST3GAL4	17 interacting genes: B2M CACYBP CD3D CD59 CD8B CDK1 HLA-A HLA-B HLA-C HLA-E HLA-G LAT LCK LGALS1 PTPRC SREK1 SRSF1
Entrez ID		926	925
HPRD ID		01725	01737
Ensembl ID		ENSG00000172116	ENSG00000153563
Uniprot IDs		P10966 Q53QL8	P01732 Q6ZVS2 Q8TAW8
PDB IDs			1AKJ 1CD8 1Q69 2HP4 3QZW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?