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CD8A

Description CD8a molecule
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
  • T Cell Receptor Complex
  • Plasma Membrane Raft
Molecular Function
  • Protein Binding
  • Coreceptor Activity
  • MHC Class I Protein Complex Binding
  • MHC Class I Protein Binding
Biological Process
  • T Cell Mediated Immunity
  • Immune Response
  • Cell Surface Receptor Signaling Pathway
  • Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
  • Antigen Processing And Presentation
  • T Cell Activation
  • Cytotoxic T Cell Differentiation
  • Regulation Of Immune Response
Pathways
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
  • Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS
  • Blood protein levels ( 30072576)
Novel Interacting Genes 2 novel interacting genes: GGCX MRPS5
Interacting Genes 17 interacting genes: B2M CACYBP CD3D CD59 CD8B CDK1 HLA-A HLA-B HLA-C HLA-E HLA-G LAT LCK LGALS1 PTPRC SREK1 SRSF1
Entrez ID 925
HPRD ID 01737
Ensembl ID ENSG00000153563
Uniprot IDs P01732 Q6ZVS2 Q8TAW8
PDB IDs 1AKJ 1CD8 1Q69 2HP4 3QZW
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025