TBRG4 and STK19

Data Source:
BioGRID (two hybrid)

		TBRG4	STK19
Description		transforming growth factor beta regulator 4	serine/threonine kinase 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Cell Cycle Arrest Positive Regulation Of Cell Population Proliferation MRNA Metabolic Process Regulation Of Mitochondrial MRNA Stability Mitochondrial MRNA Processing	Protein Phosphorylation Positive Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Colorectal cancer or advanced adenoma ( 30510241) Plateletcrit ( 32888494)	Age-related macular degeneration ( 23577725) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Broad depression or schizophrenia ( 30626913) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Disease progression in age-related macular degeneration ( 29346644) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Prostate cancer ( 23535732) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: AGTRAP BICD2 BSND CALCOCO2 CDR2L CMTM4 CMTM5 FAM114A2 FAM9B GPRASP2 HSD17B13 KRT27 LIME1 MAL2 MEOX2 PRB3 PTN RETREG3 SCAMP1 SFT2D1 STK19 TFIP11 TMEM239 TNFRSF10D	14 interacting genes: BHLHE40 MAB21L3 PFDN5 PICK1 POLE POLR2G PRAME SF3B4 SLC29A1 SP3 TBRG4 TRIM23 VIM ZRANB1
Entrez ID		9238	8859
HPRD ID		10263	07281
Ensembl ID		ENSG00000136270	ENSG00000204344
Uniprot IDs		B3KM73 B3KRS4 B4DU42 Q969Z0	A0A1U9X8L3 P49842
PDB IDs
Enriched GO Terms of Interacting Partners?
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