STK19 and SLC29A1

Data Source:
HPRD (two hybrid)

		STK19	SLC29A1
Description		serine/threonine kinase 19	solute carrier family 29 member 1 (Augustine blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Presynapse Postsynapse
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity
	Biological Process	Protein Phosphorylation Positive Regulation Of Ras Protein Signal Transduction	Neurotransmitter Uptake Nucleobase-containing Compound Metabolic Process Neurotransmitter Transport Lactation Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Sleep Adenosine Transport Excitatory Postsynaptic Potential Cellular Response To Glucose Stimulus Cellular Response To Hypoxia Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport
Pathways			Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			Troglitazone Ethanol Fostamatinib
Diseases
GWAS		Age-related macular degeneration ( 23577725) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Broad depression or schizophrenia ( 30626913) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Disease progression in age-related macular degeneration ( 29346644) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Prostate cancer ( 23535732) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908)	Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: BHLHE40 MAB21L3 PFDN5 PICK1 POLE POLR2G PRAME SF3B4 SLC29A1 SP3 TBRG4 TRIM23 VIM ZRANB1	3 interacting genes: CREB3 HTR2C STK19
Entrez ID		8859	2030
HPRD ID		07281	03724
Ensembl ID		ENSG00000204344	ENSG00000112759
Uniprot IDs		A0A1U9X8L3 P49842	Q99808
PDB IDs			6OB6 6OB7
Enriched GO Terms of Interacting Partners?
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