STK19 and PRAME

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		STK19	PRAME
Description		serine/threonine kinase 19	PRAME nuclear receptor transcriptional regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Ras Protein Signal Transduction	Apoptotic Process Positive Regulation Of Cell Population Proliferation Cell Differentiation Regulation Of Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Broad depression or schizophrenia ( 30626913) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Disease progression in age-related macular degeneration ( 29346644) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Prostate cancer ( 23535732) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Ulcerative colitis ( 28067908)
Interacting Genes		14 interacting genes: BHLHE40 MAB21L3 PFDN5 PICK1 POLE POLR2G PRAME SF3B4 SLC29A1 SP3 TBRG4 TRIM23 VIM ZRANB1	9 interacting genes: ELOB ELOC FBXO7 RARA RBX1 STK19 UBC XRN2 ZNF408
Entrez ID		8859	23532
HPRD ID		07281	05820
Ensembl ID		ENSG00000204344	ENSG00000185686
Uniprot IDs		A0A1U9X8L3 P49842	A0A024R1E6 B7Z7K8 B7Z986 B7ZAT0 P78395
PDB IDs
Enriched GO Terms of Interacting Partners?
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