GORAB and VAMP3

Data Source:
BioGRID (two hybrid)

		GORAB	VAMP3
Description		golgin, RAB6 interacting	vesicle associated membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Early Endosome Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Apical Plasma Membrane Transport Vesicle Clathrin-coated Vesicle Secretory Granule Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly	Positive Regulation Of Receptor Recycling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Positive Regulation Of Immunoglobulin Production Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Membrane Organization Membrane Fusion Protein-containing Complex Assembly Mucus Secretion Cellular Response To Interferon-gamma Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell
Pathways			ER-Phagosome pathway Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Male-pattern baldness ( 27182965 28196072) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Morning vs. evening chronotype ( 26835600) Periodontal microbiota ( 22699663) Ulcerative colitis ( 28067908)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	63 interacting genes: ACAP1 AHNAK2 AIG1 APP AQP6 ARL13B BCAP31 BCL2L13 BIK BSCL2 BSND CD79A CIAO2A CLDN7 CLEC14A COMT DDB1 DNAJC5 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B GORAB GPX8 IKBKG KCNK5 LHFPL5 LMNA MGST2 MGST3 NELFE NEMP1 PDZK1IP1 PLEKHO1 PTGES RETREG3 RMDN3 SAR1A SCN3B SLC10A1 SLC16A2 SNAP23 SNAP29 STX16 STX1A STX2 STX3 STX4 TM4SF19 TM4SF20 TMEM237 TMEM31 TMEM35A TMEM52B TMEM86B TMPPE TMX2 VAMP2 VAMP8 VEGFD VSIR
Entrez ID		92344	9341
HPRD ID		12144	04711
Ensembl ID		ENSG00000120370	ENSG00000049245
Uniprot IDs		B3KQ87 Q5T7V8	Q15836 Q6FGG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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