GORAB and STX12

Data Source:
BioGRID (two hybrid)

		GORAB	STX12
Description		golgin, RAB6 interacting	syntaxin 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Golgi Membrane Phagophore Assembly Site Nucleoplasm Golgi Apparatus Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Intracellular Membrane-bounded Organelle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways
Drugs
Diseases		Geroderma osteodysplasticum
GWAS		Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Male-pattern baldness ( 27182965 28196072) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	43 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		92344	23673
HPRD ID		12144	06059
Ensembl ID		ENSG00000120370	ENSG00000117758
Uniprot IDs		B3KQ87 Q5T7V8	Q86Y82
PDB IDs			2DNX
Enriched GO Terms of Interacting Partners?
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